Agential Topics is a n invitation-only group formed around the question of the true sources of variation in biology. The objective of these discussions is to develop rigorous, testable hypotheses about biological agency. The group includes systems theorists, working biologists, neuroscientists, entrepreneurs, philosophers, evolutionists, journalists, filmmakers, mathematicians, engineers, and a few generalist polymath scholars. Meetings are generally two hours long, discussion-based, and feature a particular reading or presentation of work from a new source.